Table 1.
Patient characteristics
| Patient | Age, months | Sex | WBC, × 103/μl | HSM | Immunophenotype | Karyotype | MLL-AF4 fusion transcript |
|---|---|---|---|---|---|---|---|
| INF-1 | 2 | F | 6 | − | B | 46,XX,t(4;11)(q21;q23)[12]/46,XX[8] | + |
| INF-2 | 4 | F | 346 | + | B | 46,XX,t(4;11)(q21;q23)[10] | + |
| INF-3 | 3 | F | 285 | + | B | Not determined | + |
| INF-4 | 1 | F | 410 | + | B | Not determined | + |
| INF-5 | 8 | M | 1,000 | + | B | 46,XY,t(4;11)(q21;q23),t(14;19)(q11.2;p13)[12]/46,XY[8] | + |
| INF-6 | 2 | F | 670 | + | B | 46,XX,t(4;11)(q21;q23)[20] | + |
| INF-7 | 3 | F | 684 | + | B | 46,XX,t(4;11)(q21;q23)[17]/46,XX[3] | + |
| INF-8 | 9 | F | 41 | + | B | 46,XX[29] | + |
| INF-9 | 2 | M | 187 | + | B | 46,XY,t(4;11)(q21;q23)[16]/46,XY[6] | + |
| INF-10 | 5 | M | 317 | + | B | Not determined | + |
| INF-11 | 2 | M | 270 | + | B | 46,XX,t(11;19)(q23;p13)[20] | − |
| INF-12 | 6 | M | 83 | − | B | Not determined | − |
MLL-AF4 fusion transcript expression was determined by RT-PCR. HSM, hepatosplenomegaly; WBC, white blood cells; INF, infant; M, male; F, female; B, B-lineage.