TABLE 2.

purI mutations and predicted amino acid changes, by mutant class

Class and allele	Mutation, at nucleotide no.a	Amino acid change
Pur− Thi−, class 1
purI2944	G-A at 755	G252D
purI2945	G-A at 755	G252D
purI3005	G-A at 386	G129D
purI3008	G-A at 386	G129D
purI3013	G-A at 386	G129D
purI3015	G-A at 755	G252D
Pur− Thi−, class 2
purI2937	C-T at 292	Q98UAG
purI3004	C-T at 245 & C-T at 850	A82V and     Q284UAA
purI3006	C-T at 625	Q209UAA
purI30014	C-T at 823	Q275UAG
Pur− Thi+
purI2938	G-A at 828	W276UGA
purI3011	C-T at 677	T226I

^aNumbering began with the first nucleotide of the purI coding region or the first amino acid of the PurI protein.