TABLE 1.
Sample | Parasitemiaa
|
% Inhibitionb in the following cells:
|
||||
---|---|---|---|---|---|---|
In patient | In assays of the following cells:
|
|||||
Control | Nm treated | Tryp treated | Nm treated | Tryp treated | ||
JB04 | 11.2 | 5.6 | 2.2 | 1.5 | 61 | 73 |
JB05 | 11.6 | 4.0 | 2.4 | 2.7 | 39 | 32 |
JB08 | 9.3 | 4.3 | 0.8 | 1.6 | 83 | 64 |
JB12 | 4.6 | 3.4 | 1.5 | 0.6 | 56 | 83 |
JB13 | 7.0 | 2.1 | 1.0 | 0.7 | 52 | 68 |
JB14 | 12.2 | 4.4 | 1.4 | 0.6 | 69 | 87 |
JB15 | 9.4 | 2.6 | 0.6 | 1.5 | 79 | 42 |
JB16 | 3.0 | 2.8 | 0.9 | 0.5 | 66 | 81 |
JB17 | 9.6 | 3.4 | 0.9 | 0.6 | 75 | 83 |
JB19 | 9.1 | 5.5 | 2.6 | 0.5 | 52 | 91 |
JB20 | 10.7 | 3.1 | 2.2 | 0.4 | 30 | 86 |
JB23 | 4.8 | 1.8 | 0.8 | 0.4 | 58 | 79 |
JB24 | 6.1 | 1.2 | 0.9 | 0.1 | 23 | 95 |
JB25 | 7.9 | 6.0 | 2.6 | 0.2 | 56 | 97 |
JB28 | 3.1 | 3.7 | 1.4 | 0.3 | 64 | 93 |
JB29 | 10.0 | 5.9 | 1.6 | 0.7 | 74 | 89 |
JB30 | 14.8 | 3.6 | 0.5 | 0.3 | 87 | 91 |
JB32 | 5.2 | 4.0 | 2.0 | 0.4 | 52 | 91 |
JB34 | 15.2 | 6.2 | 2.6 | 0.6 | 57 | 90 |
JB37 | 6.7 | 4.1 | 2.0 | 0.3 | 52 | 94 |
JB41 | 10.3 | 4.0 | 1.7 | 0.1 | 56 | 97 |
JB42 | 2.9 | 2.8 | 0.4 | 0.2 | 86 | 93 |
JB44 | 8.2 | 3.1 | 0.8 | 0.4 | 74 | 86 |
JB46 | 3.4 | 2.6 | 1.0 | 0.1 | 62 | 95 |
JB47 | 7.5 | 8.9 | 3.3 | 0.4 | 63 | 95 |
JB48 | 11.6 | 2.9 | 1.0 | 0.3 | 65 | 88 |
JB50 | 7.0 | 4.9 | 1.7 | 0.7 | 65 | 86 |
JB51 | 1.7 | 3.7 | 2.0 | 0.2 | 48 | 95 |
JB52 | 5.5 | 2.4 | 1.9 | 0.4 | 21 | 82 |
JB53 | 5.8 | 2.6 | 1.4 | 0.1 | 46 | 95 |
JB54 | 8.7 | 3.5 | 1.1 | 0.1 | 69 | 96 |
JB56 | 3.9 | 1.9 | 0.6 | 0.2 | 68 | 90 |
JB61 | 8.1 | 3.1 | 1.8 | 0.2 | 43 | 93 |
JB62 | 10.2 | 3.1 | 0.7 | 0.1 | 78 | 97 |
JB65 | 6.4 | 3.1 | 1.5 | 0.2 | 51 | 93 |
JB67 | 3.4 | 2.5 | 0.7 | 0.0 | 73 | 99 |
JB68 | 3.3 | 2.2 | 1.1 | 0.2 | 50 | 93 |
JB69 | 7.2 | 4.7 | 0.9 | 0.2 | 81 | 97 |
Calculated as the average number (from triplicate wells) of infected erythrocytes per 1,000 erythrocytes counted. Nm, neuraminidase; Tryp, trypsin.
Calculated as [1 − (parasitemia in enzyme-treated cells/parasitemia in control cells)] × 100.