TABLE 2.
SI for Gambian P. falciparum field isolates showing significant nonrandom erythrocyte invasion
Sample | Parasitemiaa | No. of parasitized erythrocytes containing the indicated no. of parasites:
|
SIc | Pd | |||||
---|---|---|---|---|---|---|---|---|---|
Observed
|
Expectedb
|
||||||||
1 | 2 | 3+ | 1 | 2 | 3+ | ||||
JB03 | 8.1 | 290 | 31 | 1 | 309 | 13 | 0 | 2.38 | <0.01 |
JB04 | 11.2 | 311 | 29 | 0 | 320 | 19 | 1 | 1.47 | 0.04 |
JB08 | 9.3 | 299 | 25 | 5 | 313 | 15 | 0 | 1.91 | <0.01 |
JB11 | 3.7 | 328 | 14 | 0 | 336 | 6 | 0 | 2.20 | <0.01 |
JB17 | 9.6 | 304 | 7 | 0 | 296 | 15 | 1 | 0.45e | 0.02 |
JB19 | 9.1 | 305 | 23 | 1 | 313 | 15 | 0 | 1.55 | 0.04 |
JB20 | 0.7 | 306 | 30 | 1 | 318 | 18 | 1 | 1.66 | <0.01 |
JB32 | 5.2 | 298 | 14 | 2 | 306 | 8 | 0 | 1.93 | 0.01 |
JB48 | 11.6 | 356 | 34 | 0 | 366 | 23 | 1 | 1.44 | 0.03 |
JB52 | 5.5 | 303 | 15 | 3 | 312 | 9 | 0 | 2.00 | <0.01 |
JB56 | 3.9 | 302 | 14 | 0 | 310 | 6 | 0 | 2.26 | <0.01 |
JB61 | 8.1 | 304 | 20 | 3 | 313 | 13 | 0 | 1.70 | 0.01 |
JB62 | 10.2 | 329 | 27 | 4 | 341 | 18 | 1 | 1.63 | 0.01 |
JB66 | 9.9 | 303 | 23 | 3 | 312 | 16 | 1 | 1.54 | 0.03 |
JB69 | 7.2 | 310 | 31 | 4 | 332 | 12 | 0 | 2.74 | <0.01 |
JB73 | 17.9 | 322 | 44 | 4 | 335 | 33 | 2 | 1.36 | 0.03 |
Calculated by examining at least 1,000 erythrocytes.
Number of parasitized cells expected in each class if invasion were a purely random process (according to a Poisson distribution).
Calculated as the observed number of cells with multiple invasions divided by the expected number.
As determined by a chi-square goodness-of-fit test of the observed numbers of erythrocytes with single and multiple invasions (pooled number of erythrocytes with two or more parasites) versus the expected numbers, with the Yates correction.
Selectivity was in the opposite direction, showing fewer erythrocytes with multiple invasions than expected.