TABLE 2.
Enhanced protection with F1-04-A-G1 and MAb 7.3 as a pretreatment against s.c. challenge
Antibody treatmenta | Y. pestis challenge MLDb | No. of survivors/group |
---|---|---|
Untreated | 46 | 0/6 |
F1-04-A-G1 + Mab 7.3 | 91 | 6/6 |
9.1 × 102 | 6/6 | |
9.1 × 103 | 5/6 | |
9.1 × 104 | 6/6 |
Mice were immunized i.p. with 35 μg of MAb 7.3 and 100 μg of F1-04-A-G1 in PBS.
Plague challenge (s.c.) 4 h after antibody administration.