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Alignment of the S. mutans LuxS protein and several other representative LuxS proteins. Residues that coordinate a Zn2+ ion and comprise the catalytic center of LuxS (H, H, and C) are printed in bold. 1, V. harveyi; 2, S. mutans; 3, E. coli; 4, S. pyogenes; 5, B. subtilis.
