FIG. 4.

Bacterial loads in the gastric mucosae of mice immunized as neonates (a) or adults (b) with a single dose of H. pylori (H.p.) antigen and CFA or IFA and challenged on day 28. Gastric biopsy samples were examined on day 56 by quantitative culture. Each symbol represents an individual mouse, and each bar represents the geometric mean of each respective group. Statistical significance of differences relative to the respective OVA-immunized control groups is indicated by single (>95% significant), double (>99% significance), or triple (>99.9% significance) asterisks.