TABLE 1.
Characteristics of mouse mammary glands and CFU counts resulting from different inocula of S. aureus 8325-4 (with FnBPs) and DU5883 (without FnBPs) bacteria mixed in equal proportions, with or without suckling pressure, after 20 h of infection
| Inoculum (CFU) | Nonsuckled glands (R4)
|
Suckled glands (L4)
|
||||||
|---|---|---|---|---|---|---|---|---|
| No. of glands | Avg no. of CFU (log) | Avg wt (g) | % DU5883 bacteria | No. of glands | Avg no. of CFU (log) | Avg wt (g) | % DU5883 bacteria | |
| 4.5 × 101 | 3 | 6.2 | 0.98 | 29.0 | 4 | 5.0 | 0.45 | 22.7 |
| 4.5 × 102 | 3 | 7.2 | 0.84 | 48.1 | 4 | 4.7 | 0.36 | 35.8 |
| 4.5 × 103 | 3 | 7.2 | 0.80 | 34.2 | 4 | 4.6 | 0.36 | 33.4 |
| 4.5 × 104 | 3 | 6.8 | 0.86 | 44.3 | 3 | 4.9 | 0.61 | 22.0 |
| Combined resultsa | 12 | 6.9 (1.0)b | 0.87 (0.17)b | 41.2 (33.8 and 44.4)c | 15 | 4.8 (0.8)b | 0.43 (0.2)b | 28.9 (20.0 and 35.4)c |
a
Individual data for all R4 or L4 glands were grouped.
b
Average (standard deviation); P < 0.001; Student t test.
c
Median (lower and upper quartiles); P < 0.05; Mann-Whitney U test