TABLE 2.
Serum IgG reactivity to multiple MSP1 block 2 repeat antigens before the transmission season is associated with protection in an incremental manner
No. of repeat antigens recognized | No. of sera | No. (%) of individuals getting malaria | Relative risk (95% confidence interval) | P value |
---|---|---|---|---|
0 | 253 | 146 (58) | 1 | |
1 | 38 | 22 (58) | 1.00 (0.75-1.34) | 0.98 |
2 | 26 | 11 (42) | 0.73 (0.46-1.16) | 0.13 |
3 | 5 | 0 (0) | 0 (∞) | 0.015 |
4 | 12 | 2 (17) | 0.29 (0.08-1.03) | 0.005 |
3 or more | 17 | 2 (12) | 0.20 (0.06-0.75) | 0.0002 |