FIG. 3.
Time course of death (A) and meningococcemia (B) in 4-day-old infant rats inoculated with different doses of the MC58 parental strain (▪) and the isogenic frp double mutant (•). Mortality experiments, performed on a total of six or seven infant animals, were repeated twice, and representative results are shown. For the meningococcemia quantification experiment, six animals were injected with inocula of 7.7 × 105 and 6 × 105 CFU for the wild-type and the frp double mutant, respectively. Bars indicate standard errors of the means.