. 2003 Apr;77(8):4679–4684. doi: 10.1128/JVI.77.8.4679-4684.2003

TABLE 3.

Presentation of bNT60 to NP_366-374-specific T_CD8+ is blocked by endosomal and phagosomal inhibitors

Treatment^a	% of T_CD8+ activated/% inhibition^b
Treatment^a	B6 mice	TAP^−/− mice
Control	6.62 (100%)	2.01 (100%)
CD	2.43/64	0/100
NH₄Cl	0.08/99	0/100

tPEC from B6 or TAP^−/− mice were exposed to cytochalasin D (CD) or NH₄Cl for 30 min prior to and during incubation with bNT60. In control experiments, inhibitors had only minor effects on the T_CD8+ activation induced by limiting amounts of peptides.

Data show the effect of inhibitors on presentation of bNT60 and are relative to control values. Similar results were obtained in two additional experiments.