TABLE 3.

Effect of MAb on CNS T-cell recruitment

Mouse typea	% CD8 T cellsb	Results for virus-specific CD8 cells		% CD4 cellsb	IFN-γ content in virus-specific CD4 cells
		Tetramer contentc	IFN-γ contentd
wt C57BL/6	15	40	1,600 ± 160	14	800 ± 60
μMT + PBS	16	13	380 ± 80	10	200 ± 36
μMT + J.2.5	17	12	460 ± 80	15	260 ± 40
μMT + J.7.2	14	15	320 ± 50	12	120 ± 50

^aMice were analyzed at day 21 p.i. Data are representative of at least three separate experiments.

^bPercentage within total CNS-derived cells.

^cPercentage of tetramer⁺ within the CD8⁺-T-cell population.

^dVirus-specific IFN-γ-secreting CD8⁺ (S510 peptide) and CD4⁺ (M133 peptide) cells per 10⁶ total cells detected by ELISPOT.