Table 4.
Sequence similarity of MHC genes between cynomolgus monkeys and humans.
MHC gene | RefSeq ID a | Nucleotide identity (%) b | Amino acid identity (%) c | Aligned exons d | |
Class I | A | NM_002116 | 84.7 | 88.6 | 3–5 |
B | NM_005514 | 86.1 | 86.5 | 1–7 | |
E | NM_005516 | 80.1 | 84.3 | 2–4 | |
F | NM_018950 | 73.9 | 75 | 4–6 | |
Class II | DMA | NM_006120 | 94 | 96.6 | 2–3 |
DOA | NM_002119 | 92 | 95 | 3–4 | |
DPA | NM_033554 | 93 | 96 | 2–5 | |
DQA | NM_002122 | 91.5 | 93 | 1–3 | |
DQB | NM_002123 | 94.6 | 95 | 2–3 | |
DRA | NM_019111 | 94 | 96 | 1–4 | |
DRB | NM_002124 | 88 | 89 | 1–4 |
a. GenBank identifiers for the human reference sequences
b. Nucleotide sequence identity between cynomolgus monkeys and humans
c. Amino acid sequence identity between cynomolgus monkeys and humans
d. Exons that MHC genes in our library aligned to the human reference sequences