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A: Immunohistochemical localisation of tight junction proteins in ureteric urothelium. Expression of claudin 3, 4, 5, 7, ZO1, occludin, E-cadherin and UPIIIa was determined by immuno-peroxidase in paraffin wax-embedded sections of normal human ureter. Sections were counterstained with haematoxylin. Scale bar = 100 μm for all except UPIIIa where scale bar = 50 μm. B: Schematic diagram of the localisation of the tight junction proteins in human urothelium.
