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Hinges and bends during functional transitions. Hinges involved in (A) the transition from the nucleotide-free to the ATP-bound state, (B) the transition from the ATP/Mg2+- to the ADP-bound state and (C) the transition from the ADP-bound to the nucleotide-free state. Hinge regions are highlighted in magenta. The catalytic domain is shown in light yellow and the helical domain in light tan. Structures shown correspond to the starting point of the functional transitions.
