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Two weeks after surgery, contraction rate (+dP/dt) (a) and relaxation rate (-dP/dt) (b) of 6 rat hearts from which biopsies were taken were compared to data obtained from 6 sham-operated rats. Data were obtained by direct LV pressure measurements using a micro-tip pressure transducer (Millar Instruments, Tx, USA) inserted into the left ventricle. Data were obtained at baseline as well as during dobutamine-stimulated conditions.
