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. 2006 Aug 1;116(8):2272–2279. doi: 10.1172/JCI28414

Figure 6. Normal GBM permeability to ferritin inCd2ap–/– mice.

Figure 6

Ferritin injections were performed in Cd2ap–/– and control littermate mice. (A and B) Total numbers of ferritin particles in the GBM at 1 and 2 hours after injection were similar in nephrotic Cd2ap–/– mice and their normal littermates at P21. However, subepithelial ferritin particle numbers were lower in the mutant, despite the albuminuria. (C–F) Representative electron micrographs showing ferritin particles in the GBM of P21 normal (C and D) and Cd2ap–/– (E and F) mice. D and F are higher magnifications of C and E, respectively. Scale bars: 125 nm.