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BSA-sensitized C57BL/6 mice were challenged i.v. with BSA at t = 0. (A) Individual MAP of mice challenged with 2, 1, or 0.1 mg BSA. (B) Individual MAP of mice pretreated with l-NAME (200 mg/kg, i.v.; –2 hours) and 0.1 mg BSA (t = 0). (C) Data points show the mean MAP ± SD of the 0.1 mg BSA plots shown in A and B. Error bars are plotted as vertical lines above and below the curves. Number of mice is indicated in parentheses. ***P < 0.0001.
