TABLE 1.
Inhibition of bacterial physiology
| Parameter | PQ concna | Activity normalized to controlb |
|---|---|---|
| Respirationc | 10 nM | 111 |
| 25 nM | 106 | |
| 50 nM | 106 | |
| 75 nM | 20 | |
| 100 nM | 11 | |
| Protein synthesis | 10 nM | 91 |
| 100 nM | 106 | |
| 1 μM | 105 | |
| 10 μM | 63 | |
| 100 μM | 30 | |
| 1 mM | 8 | |
| DNA synthesis | 10 nM | 109 |
| 100 nM | 98 | |
| 1 μM | 102 | |
| 10 μM | 56 | |
| 100 μM | 15 | |
| 1 mM | 4 |
a
Ethanol controls had values similar to the control values.
b
The control values were defined as 100.
c
Respiration was also tested by using PQ concentrations up to 25 μM, and the levels of inhibition were similar to the level of inhibition observed with 100 nM.