TABLE 2.
Inhibition of mobility of isolates by PQ
| Treatment
|
Motility of isolatesa
|
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Time (min) | PQ concn (μM) | SB1 | SB2 | SB4 | SB6 | SB8 | SB10 | SB11 | SB13 | SB14 | SB15 | SB18 | DC |
| 15 | 100 | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ |
| 10 | − | − | + | + | + | − | + | + | + | + | + | − | |
| 1 | − | − | − | − | − | − | − | − | + | − | − | − | |
| Controlb | − | − | − | − | − | − | − | − | − | − | − | − | |
| 60 | 100 | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ |
| 10 | ++ | ++ | ++ | + | ++ | − | + | + | + | + | ++ | − | |
| 1 | + | − | + | − | + | − | − | − | + | − | − | − | |
| Controlb | − | − | − | − | − | − | − | − | − | − | − | − | |
a
Motility was qualitatively scored by dark-field microscopy. −, no noticeable change in motility; +, 25 to 50% decrease in motility; ++, > 50% decrease in motility.
b
The control contained 0.08% ethanol. PQ concentrations of 1, 10, and 100 nM were also tested but had no effect.