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. 2006 Jul 19;34(12):3546–3554. doi: 10.1093/nar/gkl486

Figure 1.

Figure 1

Simplified graphical representation of the SLiMDisc method. The steps completed by SLiMDisc are in green, those which occur outside the program are in red. The input dataset is given to the TEIRESIAS algorithm for pattern discovery and the BLAST algorithm to establish the evolutionary relationships of the parent proteins. The returned motifs are then filtered according to a number of user defined criteria. Finally, the motifs are ranked using information content (based on amino acid frequencies) and evolutionary relatedness.