Table 1.
Method | Reference | Organisms | Graphic interface | Automatic processing of data | Manual annotation | Collaborative annotation | ‘Reasoning’ capabilities | Annotation assessment | Availability |
---|---|---|---|---|---|---|---|---|---|
MAGPIE | (40) | Prokaryote | No | Yes | Limited | No | Yes | No | Code available |
GENOTATOR | (41) | Eukaryote | Yes | Yes | possible | No | No | No | Code available |
GAIA | (42) | Eukaryote | Yes | Yes | Limited | No | No | No | Web use |
IMAGENE | (43) | Prokaryote | Yes | Possible | Yes | No | No | No | Availableb |
GENEQUIZ | (44) | Botha | No | Yes | No | No | Yes | Yes | Web use |
ARTEMIS | (24) | Both | Yes | No | Yes | No | No | No | GPLc |
M-AGENTS | (45) | Virus | No | Yes | No | No | No | No | Web use |
PEDANT | (46) | Both | Yes | Yes | Possible | No | No | No | Web use |
ENSEMBL | (47) | Both | Nod | Yes | Noe | Yes | No | No | GPL |
APOLLO | (48) | Both | Yes | No | Limited | Yes | No | No | GPL |
OTTER | (49) | Both | Yes | No | Yes | Yes | No | No | Code available |
RICEGAAS | (50) | Eukaryote | Yes | Yes | Limited | No | No | No | Web use |
GENQUIRE | (51) | Both | Yes | No | Yes | No | No | No | GPL |
ATUGC | (52) | Prokaryote | No | Yes | No | No | Yes | No | No |
GENDB | (53) | Prokaryote | Yes | Yes | Yes | No | Yes | No | GPL |
ASAP | (54) | Both | Yes | No | Yes | Yes | No | No | Web use |
SABIA | (55) | Prokaryote | No | Yes | No | No | No | No | Code available |
MANATEE | (see notef) | Both, virus | Yes | Yes | Yes | No | No | No | GPL |
MAGE | (56) | Prokaryote | Yes | Yes | Yes | Yes | No | No | Web use |
AGMIAL | Prokaryotes | Yes | Yes | Yes | Yes | No | No | GPL |
See the text for a detailed definition of the column headings.
aGeneQuiz carries out protein sequence analysis only. It has been mostly used to re-annotate prokaryotic genome.
bRequires ILOG licensed libraries.
cGNU public license.
dProvided by APOLLO.
ePerformed with OTTER.