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. 2003 Apr;47(4):1308–1312. doi: 10.1128/AAC.47.4.1308-1312.2003

TABLE 3.

Median inhibitory and bactericidal titers in serum of gatifloxacin and moxifloxacin over time against aerobic bacteriaa

Organism and time point (h) Gatifloxacin
Moxifloxacin
SIT (range) SBT (range) SIT (range) SBT (range)
H. influenzae
    2 1:32 (1:32) 1:32 (1:32) 1:32 (1:32) 1:32 (1:32)
    6 1:32 (1:32) 1:32 (1:32) 1:32 (1:32) 1:32 (1:16-1:32)
    12 1:32 (1:32) 1:32 (1:32) 1:32 (1:16-1:32) 1:32 (1:16-1:32)
    24 1:32 (1:16-1:32) 1:16 (1:16-1:32) 1:32 (1:16-1:32) 1:16 (1:8-1:16)
S. pneumoniae
    2 1:8 (1:8-1:16) 1:8 (1:4-1:8) 1:16 (1:16-1:32) 1:16 (1:4-1:32)
    6 1:8 (1:4-1:8) 1:4 (1:4-1:8) 1:16 (1:8-1:16) 1:8 (1:8-1:16)
    12 1:4 (1:2-1:4) 1:2 (<1:2-1:4) 1:8 (1:4-1:16) 1:8 (1:4-1:8)
    24 <1:2 (<1:2) <1:2 (<1:2) 1:4 (1:2-1:4) 1:4 (1:2-1:4)
S. aureus
    2 1:32 (1:16-1:32) 1:16 (1:4-1:32) 1:32 (1:32) 1:32 (1:16-1:32)
    6 1:16 (1:16-1:32) 1:16 (1:4-1:16) 1:32 (1:32) 1:32 (1:16-1:32)
    12 1:16 (1:8-1:16) 1:8 (1:4-1:16) 1:16 (1:16-1:32) 1:16 (1:4-1:32)
    24 1:4 (1:2-1:8) 1:2 (<1:2-1:4) 1:8 (1:8-1:16) 1:4 (1:2-1:8)
a

SIT, serum inhibitory titer; SBT, serum bactericidal titer.