Table 1.
Age, cumulative cigarette smoke consumption, and lung function data of all subjects of the study.
| Healthy | SAR | IPF | COB | |
| AGE (years) | 54 +/- 7 | 48 +/- 14 | 49 +/- 15 | 60 +/- 8 |
| NS/S/XS | 9/8/0 | 10/2/3 | 5/4/3 | 1/3/14 |
| Pack-years (PY) | 49 +/- 18 | 18 +/- 13 | 15 +/- 6 | 40 +/- 25 |
| FEV1 (%pred.) | 105 +/- 15 | 93 +/- 15 (*) | 82 +/- 23 (*) | 72 +/- 28 (**) |
| FEV1/VC (%pred.) | 91 +/- 10 | 94 +/- 6 (ns) | 94 +/- 15 (ns) | 69 +/- 19 (**) |
| RAW (kPaL-1s-1) | 0.22 +/- 0.08 | 0.16 +/- 0.1 (ns) | 0.22 +/- 0.14 (ns) | 0.28 +/- 0.16 (ns) |
| RV % TLC | 32 +/- 6 | 33 +/- 6 (ns) | 37 +/- 12 (ns) | 45 +/- 10 (**) |
| TGV (%pred.) | 112 +/- 25 | 89 +/- 23 (*) | 91 +/- 33 (ns) | 119 +/- 34 (ns) |
| VC (%pred.) | 118 +/- 13 | 102 +/- 17 (**) | 86 +/- 19 (**) | 103 +/- 25 (ns) |
| MEF75 (%pred.) | 107 +/- 35 | 92 +/- 17 (ns) | 90 +/- 45 (ns) | 52 +/- 37 (**) |
| MEF50 (%pred.) | 82 +/- 27 | 75 +/- 24 (ns) | 71 +/- 40 (ns) | 32 +/- 25 (**) |
| MEF25 (%pred.) | 62 +/- 27 | 48 +/- 22 (ns) | 51 +/- 27 (ns) | 22 +/- 18 (**) |
| TL,CO (%pred.) | 107 +/- 33 | 98 +/- 14 (ns) | 82 +/- 13 (**) | 92 +/- 21 (ns) |
Relative values of lung function parameters are given as a percentage of predicted values (% pred., [27]). Values are presented as mean +/- SD. Healthy: healthy subjects, age 40 – 65 years, SAR: patients with sarcoidosis, IPF: patients with idiopathic pulmonary fibrosis, COB: patients with chronic obstructive bronchitis. FEV1: forced expiratory volume in one second, VC: vital capacity, Raw: airway resistance, RV: residual volume, TLC: total lung capacity, TGV: thoracic gas volume, MEF25, MEF50, MEF75: maximal expiratory flow at 25, 50 and 75% of VC, respectively, TL,CO: transfer factor of the lung for carbon monoxide; ns: not significant; *: p < 0.05; **: p < 0.01.