TABLE 1.
Plate counts and mortality-specific staining for treatment of C. albicans MY2417 with amphotericin B for 10 h at 35°C, followed sequentially by treatment for 15 h at 22°C with the addition of a second antifungal agent
| Antifungal agent (concn [μg/ml]) | % of maximum fluorescence
|
No. of CFU/ml | |
|---|---|---|---|
| DiBAC4(3) | SYBR Green I | ||
| Growth control | 3.2 | 5.5 | 1.1 × 107 |
| Fluconazole (50) | 3.6 | 8.7 | 1.0 × 107 |
| Flucytosine (10) | 2.7 | 5.5 | 6.6 × 106 |
| Flucytosine (100) | 3.4 | 5.8 | 3.6 × 106 |
| Itraconazole (50) | 17.9 | 31.5 | 2.8 × 106 |
| Ketoconazole (50) | 36.5 | 58.5 | 8.5 × 105 |
| Miconazole (10) | 81.5 | 31.1 | 9.4 × 103 |
| Miconazole (20) | 76.1 | 63.6 | 8.5 × 103 |