TABLE 2.

Antiretroviral activity of a single oral bolus dose of STAMP in chronically FIV-infected cats

FIV strain, cat ID no.: (STAMP dose [mg/kg]), and laboratory parameter	Pretreatment	Posttreatment
		Wk 1	Wk 2
FIVShiz, CT1 (50)
VI-RTPBMC	2	1	1
CD4 (103/μl)	0.5	1.4	1.1
CD4/CD8 ratio	1.2	1.8	7.9
FIVVK-8, CV3 (50)
VI-RTPBMC	>5	3	4
CD4 (103/μl)	0.4	1.0	1.0
CD4/CD8 ratio	1.0	3	4
FIVPet, 93J (50)
VI-RTPBMC	4	2	3
CD4 (103/μl)	0.1	1.8	0.8
CD4/CD8 ratio	1.3	1.8	2.8
FIVBang, CV5 (100)
VI-RTPBMC	3	4	3
CD4 (103/μl)	0.2	0.7	0.7
CD4/CD8 ratio	1.1	1.6	1.7
FIVUK-8, C3D (100)
VI-RTPBMC	4	2	4
CD4 (103/μl)	0.1	0.2	0.3
CD4/CD8 ratio	0.7	1.2	1.7
FIVPet, NJ2 (100)
VI-RTPBMC	4	2	4
CD4 (103/μl)	0.2	0.5	0.5
CD4/CD8 ratio	0.7	0.8	0.9
Group (n = 6)
VI-RTPBMC	3.7 ± 0.4a	2.3 ± 0.4b	3.0 ± 0.6
CD4 (103/μl)	0.3 ± 0.1	0.9 ± 0.2b	0.7 ± 0.1c
CD4/CD8 ratio	1.0 ± 0.1	1.4 ± 0.2	1.7 ± 0.3b

^aGroup values are means ± standard deviation.

^bP < 0.005 (t test).

^cP < 0.001 (t test).