Table 3.
Potential miRNA binding sites for mouse Cx43a).
| miRNA ID | Seedb) | Seed positionc) | Humand) | ||
|---|---|---|---|---|---|
| mmu-miR-1 | UGGAAUGU | 322 | 8nt | 478 | 8nt |
| ” | 1446 | 8nt | 1609 | 8nt | |
| mmu-miR-7 | UGGAAGAC | 524 | 8nt | – | |
| mmu-miR-7b | UGGAAGAC | 524 | 8nt | – | |
| mmu-miR-15a | UAGCAGCA | 1741 | – | ||
| mmu-miR-15b | UAGCAGCA | 1741 | – | ||
| mmu-miR-16 | UAGCAGCA | 1741 | – | ||
| mmu-miR-19a | UGUGCAAA | 1225 | 495, 1377 | ||
| mmu-miR-19b | UGUGCAAA | 1225 | 495, 1377 | ||
| mmu-miR-23a | AUCACAUU | 1057 | 1211 | ||
| mmu-miR-23b | AUCACAUU | 1057 | 1211 | ||
| mmu-miR-25 | CAUUGCAC | 1727 | 8nt | – | |
| mmu-miR-30a-3p | CUUUCAGU | 969 | – | ||
| mmu-miR-30a-5p | UGUAAACA | 822 | 8nt | 971 | 8nt |
| mmu-miR-30b | UGUAAACA | 822 | 8nt | 971 | 8nt |
| mmu-miR-30c | UGUAAACA | 822 | 8nt | 971 | 8nt |
| mmu-miR-30d | UGUAAACA | 822 | 8nt | 971 | 8nt |
| mmu-miR-30e | UGUAAACA | 822 | 8nt | 971 | 8nt |
| mmu-miR-30e* | CUUUCAGU | 969 | – | ||
| mmu-miR-32 | UAUUGCAC | 1727 | – | ||
| mmu-miR-92 | UAUUGCAC | 1727 | – | ||
| mmu-miR-101a | UACAGUAC | 1032 | 8nt | 1186 | 8nt |
| mmu-miR-101b | UACAGUAC | 1032 | 8nt | 1186 | 8nt |
| mmu-miR-130a | CAGUGCAA | 1226 | 496, 1378 | ||
| mmu-miR-130b | CAGUGCAA | 1226 | 496, 1378 | ||
| mmu-miR-135a | UAUGGCUU | 641 | 793 | ||
| mmu-miR-135b | UAUGGCUU | 641 | 793 | ||
| mmu-miR-141 | UAACACUG | 328 | – | ||
| ” | 768 | – | |||
| ” | 1848 | – | |||
| mmu-miR-150 | UCUCCCAA | 1953 | 8nt | 2306,2338 | |
| mmu-miR-154 | UAGGUUAU | 1570 | – | ||
| mmu-miR-195 | UAGCAGCA | 1741 | – | ||
| mmu-miR-199a* | UACAGUAG | 1461 | – | ||
| mmu-miR-200a | UAACACUG | 328 | – | ||
| ” | 768 | – | |||
| ” | 1848 | – | |||
| mmu-miR-206 | UGGAAUGU | 322 | 8nt | 478 | 8nt |
| ” | 1446 | 8nt | 1609 | 8nt | |
| mmu-miR-216 | UAAUCUCA | 227 | 2075 | 8nt | |
| mmu-miR-218 | UUGUGCUU | 859 | 1005 | ||
| mmu-miR-221 | AGCUACAU | 949 | – | ||
| mmu-miR-222 | AGCUACAU | 949 | – | ||
| mmu-miR-224 | UAAGUCAC | 1337 | 8nt | – | |
| mmu-miR-290 | CUCAAACU | 1860 | – | ||
| mmu-miR-301 | CAGUGCAA | 1226 | 496, 1378 | ||
| mmu-miR-322 | AAACAUGA | 1381 | 8nt | – | |
| ” | 1467 | – | |||
| mmu-miR-323 | GCACAUUA | 1056 | 1210 | ||
| mmu-miR-363 | AUUGCACG | 845 | e) | ||
| mmu-miR-377 | AUCACACA | 1585 | 8nt | 2255 | 8nt |
| mmu-miR-381 | UAUACAAG | 1176 | 1323 | ||
| mmu-miR-412 | ACUUCACC | 1259 | – | ||
| mmu-miR-424 | CAGCAGCA | 1741 | – | ||
| mmu-miR-434-3p | UUUGAACC | 453 | 8nt | e) | |
| mmu-miR-466 | AUACAUAC | 55 | e) | ||
a)
Ensemble Gene ID : ENSMUSG00000050953
b)
UCUUUGGU Incomplete underlining = 7nt seed match (bases 2–8 of the miRNA)
UCUUUGGU Complete underlining = 8nt seed match (bases 1–8 of the miRNA)
All are 7nt seed match unless designated as 8nt.
c)
The first nucleotide of the seed match position in the 3′ UTR.
Number is relative to the start (+1) of the 3′ UTR.
d)
Seed conservation with human Cx43 (Ensemble Gene ID : ENSG00000152661)
e)
Ortholog of the miRNA has not been found in human.
”Additional matches for same miRNA
– Not present in the first 2500nt
*
= asterisk is part of the name of the miRNA