Table 5.
Additional findings
Childhood behavioural traits (maternal rating) | Various behaviours, particularly withdrawn, aggressive behaviour, aged 13-16, are significant predictors of the later development of psychotic symptoms and schizophrenic illness |
Schizotypal features (assessed by interviews with psychiatrist) | A combination of schizotypal features, including social withdrawal, psychotic symptoms, socio-emotional dysfunction and odd behaviour, is predictive of schizophrenia. On an individual basis, these features are not predictive |
Self-rated schizotypal cognitions | Total scores highly associated with the presence of psychotic symptoms and high scorers at increased risk of schizophrenia |
Neurodevelopmental indices | Minor physical anomalies more frequent in high risk subjects than controls. |
No relationship with psychotic symptoms or genetic liability | |
Hypertelorism | Interlens and interorbital distance greater in first episode schizophrenics and high risk subjects than controls, but not associated with psychotic symptoms or genetic liability |
Illicit drug use and life events | Cannabis and other illicit drugs associated with psychotic symptoms in high risk subjects and controls. Major life events associated with psychotic symptoms |