TABLE 1.

MIC and FICI results for the Aspergillus spp. at 24 h

Aspergillus sp. (n) and strain	End point	Concna (μg/ml) ofd:		FICI	Resultb
		CAS (alone)	ITZ (alone)			CAS (alone)	ITZ (alone)
A. fumigatus (13)
AF293	MIC	128	1	0.25	S
	MEC	0.008	0.25	2.0	1
AF1	MIC	128	0.5	0.37	S
	MEC	0.015	0.25	1.12	1
AF2	MIC	128	0.5	0.25	S
	MEC	0.015	0.25	1.5	I
AF3	MIC	128	0.5	0.25	S
	MEC	0.015	0.25	2.25	I
AF4	MIC	128	1	0.25	S
	MEC	0.06	0.25	3.0	I
AF5	MIC	128	0.5	0.25	S
	MEC	0.015	0.25	2	I
AF6	MIC	128	0.5	0.25	S
	MEC	0.03	0.25	1.5	I
AF7	MIC	128	1	0.25	S
	MEC	0.015	0.25	1.12	I
AF8	MIC	128	0.5	0.25	S
	MEC	0.015	0.25	2.25	I
AF9	MIC	128	0.5	0.25	S
	MEC	0.008	0.25	1.12	I
AF10	MIC	128	0.5	0.37	S
	MEC	0.008	0.25	1.12	I
AF11	MIC	64	0.5	0.25	S
	MEC	0.008	0.125	1.25	I
AF12	MIC	128	0.5	0.25	S
	MEC	0.03	0.25	2.12	I
A. niger (6)
ANe	MIC	16	1	0.75	Ad
	MEC	0.03	0.125	1.25	I
AN1	MIC	16	0.5	1.25	I
	MEC	0.015	0.25	1.12	I
AN2	MIC	16	1	0.75	Ad
	MEC	0.015	0.25	1.12	I
AN2	MIC	16	1	0.75	Ad
	MEC	0.015	0.25	1.12	I
AN3	MIC	32	1	0.31	S
	MEC	0.015	0.25	1.12	I
AN4	MIC	32	0.5	0.75	Ad
	MEC	0.03	0.125	1.25	I
AN5	MIC	16	1	0.75	Ad
	MEC	0.03	0.5	0.56	Ad
A. flavus (6)
Afl1	MIC	>128c	0.5	0.25	S
	MEC	0.015	0.25	2.12	I
Afl2	MIC	>128	0.5	0.25	S
	MEC	0.008	0.125	4.0	I
Afl3	MIC	>128	0.25	0.25	S
	MEC	0.03	0.06	2.5	I
Afl4	MIC	>128	0.25	0.25	S
	MEC	0.03	0.06	3.0	I
Afl5	MIC	>128	0.25	0.25	S
	MEC	0.008	0.06	2.5	I
Afl6	MIC	128	0.5	0.25	S
	MEC	0.015	0.125	3.0	I
A. terreus (6)
AT1	MIC	128	0.5	0.25	S
	MEC	0.015	0.03	1.5	I
AT2	MIC	128	0.25	0.25	S
	MEC	0.03	0.06	1.0	Ad
AT3	MIC	128	0.5	0.25	S
	MEC	0.125	0.5	0.5	Ad
AT4	MIC	128	0.5	0.25	S
	MEC	0.06	0.06	1.0	Ad
AT5	MIC	128	0.5	0.25	S
	MEC	0.06	0.06	1.5	I
AT6	MIC	128	0.5	0.25	S
	MEC	0.03	0.125	0.75	Ad

^aMIC at 24 h or MEC at 24 h observed by microscopy.

^bS, synergistic; Ad, additive; I, indifferent.

^cThe off-scale MIC of >128 μg/ml was converted to the next highest concentration, 256 μg/ml, for FICI calculation.

^dCAS, caspofungin; ITZ, itraconazole.

^eAmerican Type Culture Collection.