Table 4.
The 37 L1-up clusters (Table 1) showing the mean cluster fold change between L1 and iL3 stages, the most significant BLAST alignment and the GO slim terms, arranged by descending L1 : iL3 difference in expression.
| Cluster | Expression 1 | BLAST alignment 2 | E 2 | Accession number 2 | Gene ontology (GO) slim term 3 | ||
| Process | Function | Component | |||||
| SR01196 | 3.65 | Ce4 hypo prot5: confirmed | 2.00E-16 | Y34B4A.6 | -6 | - | - |
| SR00880 | 3.13 | Ce RPS-29 | 4.00E-28 | B0412.4 | embryogenesis & morphogenesis | - | ribosome |
| SR01112 | 2.87 | -6 | - | - | - | - | - |
| SR00783 | 2.78 | Ce RPS-21 | 2.00E-33 | F37C12.11 | protein biosynthesis | constituent of ribosome | ribosome |
| SR00048 | 2.77 | Ce RPL-30 | 2.00E-39 | Y106G6H.3 | - | - | - |
| SR02498 | 2.77 | - | - | - | - | - | - |
| SR00689 | 2.64 | Ce RPL-38 | 7.00E-17 | C06B8.8 | protein biosynthesis | RNA binding, constituent of ribosome | ribosome |
| SR02484 | 2.57 | - | - | - | - | - | - |
| SR01003 | 2.54 | Ce RPS-14 | 1.00E-79 | F37C12.9 | protein biosynthesis & metabolism | - | ribosome |
| SR01012 | 2.50 | Ce RPS-15 | 8.00E-67 | F36A2.6 | embryogenesis & morphogenesis | - | - |
| SR00216 | 2.43 | Ce hypo prot: confirmed | 2.00E-33 | C14A4.1 | embryogenesis & morphogenesis | - | phycobilisome |
| SR00059 | 2.38 | Ce RPS-10 | 4.00E-42 | D1007.6 | embryogenesis & morphogenesis | - | - |
| SR00938 | 2.38 | Ce RPL-33 | 2.00E-37 | F10E7.7 | - | tRNA binding | - |
| SR00178 | 2.35 | Ce hypo prot: predicted | 7.00E-12 | VK10D6R.1 | - | - | - |
| SR02516 | 2.35 | Ce VHA-2 | 3.00E-16 | P34546 | proton transport | - | integral to membrane |
| SR00926 | 2.31 | Ce RPL-23 | 2.00E-76 | B0336.10 | protein biosynthesis & metabolism | - | ribosome |
| SR00943 | 2.31 | Ce RPL-14 | 4.00E-44 | C04F12.4 | embryogenesis & morphogenesis | - | ribosome |
| SR00211 | 2.30 | Ce RPL-31 | 4.00E-45 | W09C5.6a | protein biosynthesis | constituent of ribosome | ribosome |
| SR00804 | 2.30 | Ce RPS-11 | 5.00E-62 | F40F11.1 | embryogenesis & morphogenesis | - | ribosome |
| SR00871 | 2.30 | Ce LYS-4 | 6.00E-60 | F58B3.1 | - | - | - |
| SR00951 | 2.28 | Ce RPL-37 | 1.00E-39 | W01D2.1 | - | - | - |
| SR01225 | 2.28 | Ce hypo prot: confirmed | 3.00E-41 | C30C11.1 | protein biosynthesis | - | mitochondrial ribosome |
| SR00012 | 2.27 | Ce COL-34 | 1.00E-15 | F36A4.10 | - | - | - |
| SR02773 | 2.27 | Ce adenylate kinase | 1.00E-92 | P34346 | - | adenylate kinase activity | - |
| SR01008 | 2.23 | Ce RPS-26 | 9.00E-61 | F39B2.6 | larval development | - | - |
| SR01007 | 2.22 | Ce RPS-4 | 1.00E-111 | Y43B11AR.4 | protein biosynthesis | constituent of ribosome | ribosome |
| SR00978 | 2.20 | Ce RPS-13 | 2.00E-80 | C16A3.9 | protein biosynthesis | constituent of ribosome | ribosome |
| SR01030 | 2.20 | Ce RPS-5 | 3.00E-108 | T05E11.1 | protein biosynthesis | constituent of ribosome | ribosome |
| SR00801 | 2.18 | Ce hypo prot: confirmed | 9.00E-53 | Y82E9BR.3 | - | - | integral to membrane |
| SR00915 | 2.08 | Ce RPL-29 | 1.00E-18 | B0513.3 | protein biosynthesis | RNA binding, constituent of ribosome | ribosome |
| SR01068 | 2.07 | Ce RPL-1 | 4.00E-110 | Y71F9AL.13a | protein biosynthesis | constituent of ribosome | ribosome |
| SR02436 | 2.07 | Ce hypo prot: confirmed | 1.00E-57 | Q9U330 | dephosphorylation, phosphoinositide metabolism, dephosphorylation | inositol/phosphatidylinositol phosphatase activity | integral to golgi and endoplasmic reticulum membrane |
| SR00026 | 2.06 | Ce4 RPA-1 | 2.00E-45 | Y37E3.7 | - | - | - |
| SR00886 | 2.06 | Ce RPL-34 | 1.00E-32 | C42C1.14 | protein biosynthesis | constituent of ribosome | ribosome |
| SR00811 | 2.04 | Ce RPS-20 | 9.00E-52 | Y105E8A.16 | protein biosynthesis & metabolism | - | ribosome |
| SR00588 | 2.04 | Ce COL-156 | 2.00E-76 | F57B7.3 | cuticle biosynthesis | constituent of cuticle | extracellular |
| SR02281 | 2.00 | Ce hypo prot: confirmed | 3.00E-40 | Q21732 | - | - | - |
1The mean cluster L1 : iL3 difference in expression.
2 The most significant BLAST alignment for each cluster, the BLAST score, E, and GenBank accession number.
3Gene ontology slim term, [52].
4 Ce: C. elegans
5hypo prot – hypothetical protein; predicted – ORF predicted by GeneFinder in WormBase [53]; partially confirmed – partial sequence cloned; confirmed – full-length sequence cloned.
6- = no assignment or alignment, as appropriate.