Skip to main content
. 2003 Apr;47(4):1376–1381. doi: 10.1128/AAC.47.4.1376-1381.2003

TABLE 1.

Independently determined MICs for the Y and M forms of dimorphic fungi

Organism MIC (μg/ml)a
MCFG AMB ITC FLC
H. capsulatum
    IFM41612 >64/0.0625 0.25/0.125 0.0156/0.0156 2/4
    IFM41329 >64/0.0313 0.25/0.0625 0.0078/0.0313 2/16
    IFM41330 >64/0.0313 0.125/0.125 ≤0.0039/0.0313 4/16
    G217B >64/NTb 0.5/NT 0.0156/NT 1/NT
B. dermatitidis
    ATCC 26197 >64/0.0078 0.125/0.0156 ≤0.0039/0.0078 2/16
    ATCC 26198 >64/0.0156 0.125/0.0156 0.0156/0.0078 4/32
    ATCC 26199 32/0.0313 0.125/0.0156 0.0078/0.0313 1/32
    IFM40753 NT/0.0156 NT/0.0156 NT/0.0156 NT/32
    IFM40754 32/0.0156 0.125/0.0156 ≤0.0039/0.0313 4/32
    IFM41634 64/0.0078 0.125/0.0156 ≤0.0039/0.0078 1/32
P. brasiliensis
    IFM41620 >64/16 0.25/0.0156 ≤0.0039/≤0.0039 0.25/0.5
    IFM41621 >64/16 0.25/0.0078 ≤0.0039/≤0.0039 0.5/0.5
    IFM41626 >64/8 0.0625/0.0156 ≤0.0039/≤0.0039 0.25/1
    IFM41632 >64/16 0.125/0.0313 ≤0.0039/≤0.0039 0.125/0.25
    IFM41633 >64/8 0.125/0.0313 ≤0.0039/≤0.0039 0.125/1
    IFM46215 >64/4 0.25/0.0156 ≤0.0039/0.0078 0.5/1
    IFM46930 >64/4 0.25/0.0625 ≤0.0039/≤0.0039 0.25/1
P. marneffei
    IFM41707 16/NT 0.25/NT 0.0156/NT 2/NT
    IFM41708 16/0.0313 0.25/0.25 0.0313/0.0625 2/4
    IFM47279 16/2 0.5/0.25 0.0313/0.0156 2/2
    IFM47280 8/2 0.25/0.125 0.0156/0.0078 1/2
    IFM47281 4/2 0.25/0.25 0.0156/0.0156 1/4
S. schenckii
    IFM46011 >64/NT 0.5/NT 1/NT 16/NT
    IFM46605 64/NT 1/NT 2/NT >64/NT
    IFM46927 16/1 1/1 2/0.5 >64/>64
    IFM47068 >64/0.5 1/1 2/1 >64/>64
    IFM46989 NT/1 NT/2 NT/1 NT/>64
    IFM47069 NT/1 NT/2 NT/1 NT/>64
    IFM46990 NT/1 NT/1 NT/1 NT/>64
C. immitis
    IFM4935 NT/0.0156 NT/0.25 NT/0.0625 NT/4
    IFM4945 NT/0.0156 NT/0.25 NT/0.125 NT/4
    IFM45816 NT/0.0156 NT/0.0625 NT/0.0625 NT/4
    IFM45868 NT/0.0156 NT/0.25 NT/0.125 NT/4
a

MICs were determined as minimum drug concentrations resulting in prominent growth inhibition compared with the growth control.

b

NT, not tested.