Table 1.
Demographics, stroke risk factors and clinical characteristics of the study population.
| Acetaminophen (n = 26) | Ibuprofen (n = 24) | Placebo (n = 25) | |
| Demographics | |||
| Age in years (m, SD) | 69 (16) | 67 (15) | 65 (10) |
| Male sex | 17 (65%) | 16 (67%) | 16 (64%) |
| Risk factors for stroke | |||
| Hypertension | 12 (46%) | 7 (29%) | 8 (32%) |
| Atrial fibrillation | 6 (24%) | 7 (29%) | 1 (4%) |
| Peripheral vascular disease | 4 (15%) | 1 (4%) | 1 (4%) |
| Diabetes mellitus | 1 (4%) | 4 (17%) | 3 (12%) |
| Previous TIA | 5 (19%) | 3 (13%) | 3 (12%) |
| Previous stroke | 3 (12%) | 8 (33%) | 2 (8%) |
| Cigarette smoking | 14 (54%) | 13 (54%) | 16 (64%) |
| Stroke characteristics | |||
| Lowered consciousness level | 5 (19%) | 2 (8%) | 2 (8%) |
| Aphasia | 7 (27%) | 9 (37%) | 6 (24%) |
| NIHSS (m, SD) | 18 (14) | 12 (10) | 14 (11) |
| Lacunar stroke | 8 (31%) | 6 (25%) | 11 (44%) |
| Other clinical characteristics | |||
| Treatment within 0–12 hours | 14 (54%) | 14 (58%) | 12 (48%) |
| Temp. at admission (°C) (m, SD) | 37.2 (0.6) | 37.0 (0.6) | 37.0 (0.5) |
| Temp. at start of treatment (°C) (m, SD) | 37.3 (0.5) | 37.1 (0.7) | 37.0 (0.5) |
Acetaminophen is given in a dose of 1000 mgs, 6 times daily, and ibuprofen in a dose of 400 mg 6 times daily. Values are absolute numbers with percentages of totals in the treatment arms, unless stated otherwise. 'm' indicates mean, 'SD' standard deviation.