Figure 5.
Effect of cJun on PGC-1α and HNF4α co-activation of human CYP7A1 promoter activity- Human CYP7A1 promoter/luciferase construct (ph-298/luc, 1μg) was transfected into HepG2 cells. The expression plasmids for cJun, dncJun, PGC-1α and HNF4α were cotransfected in the concentrations indicated in A and B. The error bars represent the standard deviation from the mean of triplicate assays of an individual experiment. N=3. *, statistically significant (P<0.05).