TABLE 1.
Summary of radiation sensitivity and homologous recombination in RNAi lines or mutants of 14 SWI2/SNF2 genes
| Observed functionc
|
||||||
|---|---|---|---|---|---|---|
| Gene | CHRa | Homologb | Predicted function | γ-IR | UV-C | ICR Rate |
| At3g19210 | CHR25 | RAD54 | DNA repair and homologous recombination | S | S | WT |
| At2g18760 | CHR8 | ERCC6/RAD26 | Excision repair and/or transcription-repair coupling | WT | S | WT |
| At1g08600 | CHR20 | ATRX | Transcriptional regulator | S | S | WT |
| At2g25170 | CHR6 | PICKLE/GYMNOS | Regulation of multiple gene families | S | S | WT |
| At2g13370 | CHR5 | ND | Unknown | WT | S | WT |
| At5g63950 | CHR24 | ERCC6/RAD26 | Excision repair and/or transcription-repair coupling | S | S | ND |
| At5g44800 | CHR4 | hMi-2-LIKE | Human mi-2 autoantigen-like for dermatomyositis | S | R | Reduced |
| At5g66750 | CHR1 | DDM1 | Maintenance of DNA methylation 1 | S | S | WT |
| At2g46020 | CHR2 | AtBRM | Controls shoot and flower development | S | ND | Reduced |
| At2g02090 | CHR19 | ETL1 | Transcriptional regulation and DNA repair | WT | WT | WT |
| At1g05490 | CHR31 | ND | Unknown | WT | R | WT |
| At1g03750 | CHR9 | ND | Unknown | S | WT | WT |
| At3g24340 | CHR40 | ND | Unknown | WT | WT | WT |
| At3g12810 | CHR13 | PIE1/SRCAP | Required for FLC activation and floral repression | S | R | WT |
The CHR number corresponds to the chromatin remodeling gene number given in the Plant Chromatin Database (http://www.chromdb.org).
The name of the homolog is given or of the gene itself (underlined) whenever it has been previously characterized.
The response of the RNAi or both RNAi and mutant (in italics) plants to γ-irradiation (γ-IR) or UV-C (254 nm) is indicated as sensitive (S), resistant (R), similar to wild type (WT), or not determined (ND). The intrachromosomal recombination rate (ICR) is indicated as similar or reduced compared to WT. For GYMNOS, two mutant alleles and one RNAi line were tested and gave the same results. For At5g63950, only the mutant line was tested.