Figure 1.

mnm loss-of-function is a dominant enhancer of hedgehog loss-of-function in the compound eye. (A–F) Scanning electron micrographs of adult female compound eyes: dorsal, up; anterior, right and to the same scale (indicated in F). (A) hh⁸/hh⁺, phenotypically indistinguishable from wild type; (B) hh^bar3/hh^bar3, has a rough and reduced eye; (C) hh⁸/hh^bar3, has a slightly rough and reduced eye; (D) mnm¹/+; hh⁸/hh^bar3; (E) mnm^P/+; hh⁸/hh^bar3; (F) mnm^PX1/+; hh⁸/hh^bar3. Note that the hedgehog eye phenotype is enhanced by mnm loss-of-function. (G) Quantification of facet counts; also see materials and methods. The number in each bar is the mean number of facets and the letter identifies which genotype and section (as above) it refers to. Error bars are standard deviation. ***P < 0.005; **P < 0.01.