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. 2005 Dec 28;8(1):R18. doi: 10.1186/ar1871

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Copyright © 2005 Ernestam et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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IL-15 is present in synovial tissue in rheumatoid arthritis before and after treatment with infliximab. Sections of synovial biopsy tissue from patient no. 5 show diaminobenzidine staining (haematoxylin counterstained) for IL-15 neutralizing antibody before (a) and after (b) treatment with infliximab, and for IL-15 non-neutralizing antibody before (c) and after (d) treatment with infliximab. In (a) and (c) solid arrows indicate synovial lining layer and dotted arrows indicate endothelial cells. Original magnification × 250.