Table 3.
TNFα levels in high and low TNFα producing patient users and nonusers of antimalarial treatment
TNFα genotype | Healthy controls | Patients without antimalarial drugs | Patients with antimalarial drugs | p | |||
n | TNFα (pg/ml)a | n | TNFα (pg/ml)a | n | TNFα (pg/ml)a | ||
High (AA/AG) | 53 | 20.06 (125.63) | 24 | 83.55 (171.64) | 48 | 16.88 (54.89) | 0.001 |
Low (GG) | 162 | 18.83 (40.67) | 45 | 58.56 (168.94) | 54 | 26.00 (154.67) | 0.516 |
aValues are median (interquartile range). Differences between users and nonusers of antimalarial therapy were evaluated by the Mann-Whitney U test. TNF, tumor necrosis factor.