Table 5.
IL-10 and TNFα genotypes of systemic lupus erythematosus patients stratified by treatment
| Treatment | TNFα genotype | IL-10 genotype | ||
| High (AA/AG) | Low (GG) | High (GG) | Low (AA/AG) | |
| None/NSAIDS | 6 (26.1) | 17 (73.9) | 4 (17.4) | 19 (82.6) |
| Antimalarials | 23 (57.5) | 17 (42.5) | 6 (15.0) | 34 (85.0) |
| Corticosteroids | 8 (28.6) | 20 (71.4) | 6 (22.2) | 21 (77.8) |
| Antimalarials and corticosteroids | 25 (41.7) | 35 (58.3) | 16 (26.7) | 44 (73.3) |
| Immunosuppressive drugsa alone or with corticosteroids | 13 (48.1) | 14 (51.9) | 3 (11.1) | 24 (88.9) |
| Antimalarials, corticosteroids and immunosuppressive drugsa | 5 (35.7) | 9 (64.3) | 3 (21.4) | 11 (78.6) |
Values are n (%). aMethotrexate, azathioprine, cyclophosphamide, cyclosporine A or mycophenolate mophetil. NSAIDS, nonsteroidal anti-inflammatory drugs; TNF, tumor necrosis factor.