Table 1.
Leukocyte accumulation in inflammatory exudates
Mouse group | Peritoneal exudate (× 106cells ± SEM) |
A2A wild type | 9.3 ± 0.6 (n = 14) |
A2A knockout | 9.2 ± 0.8 (n = 14) |
A3 wild type | 10.6 ± 0.5 (n = 19) |
A3 knockout | 12.5 ± 0.4* (n = 23) |
Inflammatory exudates were induced in the peritoneum of knockout and wild-type mice, as described. After 4 hours the exudates were collected and the leukocytes quantitated. The wild-type control mice were derived from the same heterozygous breeding pairs and were matched for age and sex. There was no difference in the number of leukocytes accumulating in the exudates of male vs female mice in either the knockout mice or wild-type mice. *P < 0.005 vs A3 wild-type mice, Student's t test.