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Analysis of cell populations by flow cytometry
| C57BL/6 (n = 3) | ash.DNase I (n = 5) | P | |
| Spleen | |||
| CD4+ of all lymphocytes (%) | 18.1 ± 1.4 | 18.0 ± 1.6 | NS |
| B/T ratio | 6.3 ± 0.2 | 5.7 ± 1.0 | NS |
| CD4/CD8 ratio | 1.6 ± 0.1 | 1.5 ± 0.2 | NS |
| CD4+ expressing CD62L+ (%) | 73.2 ± 2.6 | 72.8 ± 3.1 | NS |
| Thymus | |||
| CD4/CD8+ lymphocytes (%) | 81.6 ± 1.5 | 79.8 ± 2.4 | NS |
| CD4+ CD8- lymphocytes (%) | 3.6 ± 0.3 | 3.9 ± 0.4 | NS |
ash.DNase I = actin-resistant, salt-resistant and hyperactive mutant of DNase I; NS, not significant.
