TABLE 3.
Ray 1 axon defects
| Ray axon morphology
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|---|---|---|---|---|---|---|---|---|
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| Genotype | Wild type (%) | Wandering (%) | Ectopic outgrowth (%) | No ventral turning (%) | Anteriorly ventral turn (%) | Bifurcating (%) | Cell migration (%) | N |
| him-5(e1490) | 97 | 2 | 0.4 | 228 | ||||
| rax-1(bx126) | 51 | 11 | 26 | 3.3 | 8.5 | 274 | ||
| rax-1(bx132) | 20 | 16 | 49 | 3.9 | 8.1 | 405 | ||
| rax-4(bx139) | 39 | 2 | 48 | 5 | 6 | 288 | ||
| rax-2(bx131) | 82 | 16 | 2 | 100a | 84 | |||
| rax-3(bx133) | 73 | 27b | 78 | 101 | ||||
| rax-3(bx138) | 81 | 19b | 77 | 170 | ||||
| rax-5(bx137) | 70 | 7 | 13 | 10 | 17c | 225 | ||
| rax-6(bx140) | 77 | 7 | 16 | 48c | 109 | |||
| bx141 | 73 | 27 | 68 | |||||
| sax-2(bx130) | 100 | 200 | ||||||
| unc-27(bx124) | 9 | 79 | 12 | 153 | ||||
The percentage of sides with ray 1 defect is shown. Defects in the ray 1 process were the most easily scored and most likely to be abnormal. With the exception of rax-1 and rax-4, ray commissures of the posterior rays were usually present in mutants.
a
80% of males have more than 8 pkd-2∷GFP positive neurons in the tail, in addition to the anterior mispositioned ray neuons.
b
Ray axons from 27% and 19%of sides in bx133 and bx138 mutant, respectively, fail to make the ventral turn when the neurons are mispositioned anteriorly. The rest of the neurons extend posteriorly-directed axons.
c
The neurons of fused rays form cluster in the lumbar ganglion. Axon defects and cell migration defect are counted separately.