Fig. 5. Comparison of the 3D models of T.thermophilus AspRS-2 and of P.kodakaraensis AspRS (ATP form, Schmitt et al., 1998). (A) Superimposition of subunit A of AspRS-2 (green) and subunit A from P.kodakaraensis AspRS (red). Surface residues of the AspRS-2 active-site domain that show largest structural deviations with P.kodakaraensis AspRS are in italics. (B) Values of r.m.s. deviations calculated by least squares minimized superimposition of the active-site domains. Notice that the N-terminal domain of AspRS-2 deviates from that of P.kodakaraensis AspRS by a rigid body rotation of 4°.