Fig. 8. Mutants of P.aeruginosa for the homologues of the genes disrupted in the Db11-derived mutants 10E5 and 7F1 (PA14-M151 and PA14-M3713, respectively) are attenuated in C.elegans. Kinetics of killing of C.elegans infected by P.aeruginosa strain PA14 (closed squares), PA14 mutant M151 (open circles) and PA14 mutant M3713 (open triangles). Worms were grown on NGM plates at 20°C, and 40–50 N2 hermaphrodites were used in each test. The curves are representative of at least two independent trials. The differences between PA14 and M151 or M3713 are statistically significant (p < 0.0004 and p < 0.023, respectively).