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MAP (a) and plasma IR-γ-MSH concentration (b) after 1 week of a LSD or HSD in Mc3r+/+ and Mc3r–/– mice. Results are means ± SEM of MAP in five mice in each group and of IR-γ-MSH concentration in five samples of plasma, each pooled from three mice. *P < 0.001 versus all other values.
