Skip to main content
. 2003 Apr 15;111(8):1107–1113. doi: 10.1172/JCI18338

Figure 2.

Figure 2

Membrane topology of proteins involved in eicosanoid synthesis. The active sites of LTC4 synthase, COX1, COX2, and the lipid-binding domain of FLAP are all oriented to the lumen of the ER and the nuclear envelope.