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. 2003 Mar 17;100(7):4078–4083. doi: 10.1073/pnas.0737556100

Figure 3.

Figure 3

Parkin function is required in mesoderm for normal wing posture, flight, and locomotion. (A and A′) Wing posture in 1-day-old control flies (parkrvA/Df(3L)Pc-MK) and (B and B′) age-matched parkin mutants (park25/Df(3L)Pc-MK) showing the downturned wing phenotype of parkin mutants. (C and D) parkin mutants exhibit impaired flight and climbing ability relative to control flies (see Methods for details). All flies tested were transheterozygous for the Df(3L)Pc-MK deletion and the parkin allele indicated. (E and F) Ectopic expression of parkin in mesoderm with the 24B-GAL4 (24) or Dmef2-GAL4 (21) driver restores flight and climbing ability in parkin mutants. All flies tested were transheterozygous for the Df(3L)Pc-MK deletion and the parkin allele indicated. Genotypes: Rescue 1: w; UAS-park/+; park13/24B-GAL4, Df; Rescue 2: w; UAS-park/+; park13/Dmef2-GAL4, Df; Control 1: w; park13/Dmef2-GAL4, Df; Control 2, w; park13/24B-GAL4, Df; Control 3: w; UAS-park/+; park13/Df. Error bars indicate the SEM.