Figure 4.

Effects of slit-diaphragm length on serum albumin concentration and urinary albumin excretion in 14 patients with minimal-change nephrotic syndrome. The data points are from Bohman et al. (18). CR, patients in complete remission with normal serum albumin and no proteinuria; IR, patients in incomplete remission with low serum albumin but no proteinuria; HP, patients with low serum albumin and heavy proteinuria. The blue and red lines show the simulated serum albumin concentrations and the simulated albumin excretion, respectively. Serum albumin and slit-diaphragm lengths are relative to the means of the three patients in complete remission (+). The albumin excretion is relative to that predicted by the simulation when the slit-diaphragm length is 20% normal (X).