Figure 4.

Specific localization of p95-C2 at large Rab11-positive vesicles. Neurons expressing p95-C2 were costained with antibodies against markers for distinct intracellular compartments. P95-C2 colocalized with the recycling endosomal marker Rab11 (A and B), whereas no colocalization was evident with the early endosomal marker EEA1 (D and E), the lysosomal marker LEP100 (F and G), and the Golgi marker βCOP (H–I). In C is shown the normal appearance of the Rab11 compartment in untransfected retinal neurons. Bar, 5 μm.