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In vitro phosphatase activity of wild type and mutant full-length Inp53 proteins fused to GST
| Relative amount of phosphate released
|
||
|---|---|---|
| PtdIns(4)P | PtdIns(4,5)P2 | |
| GST | 3.07 ± 0.04 | 63 ± 3 |
| GST-Inp53 | 4.29 ± 0.04 | 384 ± 16 |
| GST-Inp53-sac1 | 2.81 ± 0.05 | 566 ± 44 |
| GST-Inp53-5ptase1 | 3.55 ± 0.08 | 66 ± 10 |
