OXPHOS analysis of 4- to 6-day-old Sod2−/− mice vs. controls. Open bars, Sod2+/+ and -±; closed bars, Sod2−/−. Complexes I, II+III, III, and IV and citrate synthase (CS) are shown for mitochondria isolated from skeletal muscle and heart. SEMs are shown. n = 11 for controls; n = 9 for Sod2−/− mice. (a) OXPHOS enzymology from skeletal muscle. (b) OXPHOS enzymology from heart.